CHIRON is a European Research Project co-financed by the ARTEMIS Joint Undertaking (call 2009 – Artemis Sub-program ASP2: Person-centric Healthcare). The CHIRON Project combined state-of-the art technologies and innovative solutions into an integrated framework designed for an effective and person-centric health management along the complete care cycle. CHIRON aimed to harmonize the needs and interests of all the three main beneficiaries of the healthcare process, i.e., the citizens using the services, the medical professionals and the whole community. Furthemore, CHIRON enlarged the boundaries of healthcare by fostering a seamless integration of clinical setting, at home setting and mobile setting in a concept of a continuum of care.